close [X]

Sep 30, 2021

USDA Vaccine Successfully Blocks ASF Spread

Vaccine candidates have been shown to prevent, protect European and Asian swine

source: U.S. Department of Agriculture's (USDA) Agricultural Research Service (ARS)

The U.S. Department of Agriculture's (USDA) Agricultural Research Service (ARS) announced that one of its African Swine Fever Virus (ASFV) vaccine candidates has been shown to prevent and effectively protect both European and Asian bred swine against the current circulating Asian strain of the virus.

The majority of swine used in the global food supply are produced in Asia, where the virus has been causing outbreaks and devastating losses to the swine industry.

African Swine Fever (ASF) was originally detected in 2007 in the Republic of Georgia and is known to cause virulent, deadly disease outbreaks in wild and domesticated swine.

Since the original outbreak, ASF has had a widespread and lethal impact on swine herds in various countries in Eastern Europe and throughout Asia.

Although the virus is causing profound economic losses to the swine industry, there have not been any outbreaks in the United States. The virus is unable to transmit from pigs to humans.

Newly published USDA research, as highlighted in the journal Transboundary and Emerging Diseases, shows that ARS scientists have developed a vaccine candidate with the ability to be commercially produced while still maintaining its vaccine efficacy against Asian ASFV strains when tested in both European and Asian breeds of swine.

The findings also show that a commercial partner can replicate experimental level results and prevent the spread of the virus.

Previous studies were done under laboratory conditions only in European-bred pigs using an ASFV isolate, or sample, from the initial outbreak.

"We are excited that our team's research has resulted in promising vaccine results that are able to be repeated on a commercial level, in different pig breeds, and by using a recent ASFV isolate," says ARS researcher Douglas Gladue.

"This signals that the live attenuated vaccine candidate could play an important role in controlling the ongoing outbreak threatening the global pork supply," says ARS researcher Douglas Gladue.

The onset of immunity was revealed in approximately one-third of the swine by second week post-vaccination, with full protection in all swine achieved by the fourth week.

A commercial vaccine for ASFV will be an important part of controlling ASFV in outbreak areas. Researchers will continue to determine the safety and efficacy of the vaccine under commercial production conditions and are closely working with their commercial partner in Vietnam.

"This is a major step for science and agriculture," says ARS researcher Manuel Borca. "We are working carefully to see our vaccine candidate commercialized through the joint efforts of the U.S. government, and our commercial partner, the Navetco National Veterinary Joint Stock Company."

To date, ARS has successfully engineered and patented five ASF experimental vaccines and has fully executed seven licenses with pharmaceutical companies to develop the vaccines. ARS continues to evaluate additional commercial partners to develop these vaccines.

The Agricultural Research Service is the U.S. Department of Agriculture's chief scientific in-house research agency.

Recently Added to Buyer's Guide

Ultra Scoop

  • 20,000 bushels/hour
  • 40-foot inclined conveyor

TruGro Weight Management for Pets

  • Plant-based ingredient solution for pet food, treats, and supplements
  • Standardized, polyphenol-rich botanical extracts containing compounds naturally occurring in green tea leaves

Access Platforms

  • Anti-slip access platforms to reach elevated process equipment safely
  • Modular system includes braced frames which can be bolted to floor

HP FiberBoost©

  • Contains functional fibers produced specifically for dietetic use in piglets
  • Fiber stimulates gut and eases transition at weaning

Huve Check-Feed

  • On-site screening test to detect monensin, including Monovet® 90, in feedstuffs
  • Produces accurate, reliable results without adding microtracer particles to feed for detection methods

VM-13.3 G

  • Industrial-grade 13.3-inch LCD monitor
  • Full HD resolution: 1920 x 1080 (1080p/60)

Magazine

Marketwatch: Dec, 03

cmdty National Corn Price Idx: ZCPAUS.CM

open: 5.6309
high: 5.6797
low: 5.6159
close: 5.6309

cmdty National Soybean Price Idx: ZSPAUS.CM

open: 11.9852
high: 12.1581
low: 11.9477
close: 12.111

cmdty National Hard Red Winter Wheat Price Idx: KEPAUS.CM

open: 8.119
high: 8.2535
low: 8.054
close: 8.2002

cmdty National Soft Red Winter Wheat Price Idx: ZWPAUS.CM

open: 7.5939
high: 7.7096
low: 7.5239
close: 7.6525